JEUVEAU®

Jeuveau (prabotulinumtoxinA-xvfs) is an FDA-approved injectable treatment that temporarily smooths moderate to severe glabellar lines, the frown lines between the eyebrows, lateral brow lines, bunny lines (from crinkling the nose), chin wrinkles, crow’s feet, a gummy smile, lip lines, and neck bands.

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WHAT CAN JEUVEAU® DO

It may be used by qualified providers for other aesthetic concerns, including:

  • Forehead lines
  • Crow’s feet
  • Bunny lines
  • Chin dimpling
  • Lip lines
  • Gummy smile
  • Neck bands

WHAT TO KNOW

Before and After Treatment

Pre – Treatment

  • Arrive with the treatment area clean and free of makeup.
  • Inform your provider about any medications, supplements, allergies, or medical conditions.
  • Tell your provider about any previous botulinum toxin treatments.
  • Let your provider know if you are pregnant, breastfeeding, or planning to become pregnant.
  • Discuss your treatment goals and areas of concern with your injector.

Post – Treatment

  • Avoid rubbing or massaging the treated areas immediately after treatment.
  • Avoid strenuous exercise and excessive heat for the period recommended by your provider.
  • Temporary redness, swelling, tenderness, or bruising at injection sites may occur.
  • Results typically begin to appear within a few days and continue to develop.
  • Follow your injector’s personalized aftercare instructions.
  • Contact your provider if you experience any unexpected or concerning symptoms.

Frequently Asked Questions

When injected, Jeuveau temporarily prevents your nerves from telling your facial muscles to flex. The result? In clinical trials, Jeuveau was shown to temporarily improve the appearance of moderate to severe frown lines.

In clinical trials, Jeuveau was shown to temporarily improve the appearance of moderate to severe frown lines. In US studies, 68% and 70% of Jeuveau patients had a 2-grade or better physician- and patient-rated improvement in frown lines at Day 30. But that's not all. In a study conducted in Europe and Canada, 54% of patients had visible results as early as 2 days after treatment.* And at 5 months after treatment, 38% of patients had visible results with Jeuveau**

*54% of Jeuveau patients had a ≥1-grade improvement in frown lines at Day 2 based on physician assessment compared to 12% for placebo (secondary endpoint). In US studies, 46% and 56% had a ≥1-grade improvement in frown lines at Day 2 based on physician assessment compared to 8% and 17% for placebo (exploratory endpoint). Results based on a 1-grade improvement may not be clinically meaningful.

*38% of Jeuveau patients had a ≥1-grade improvement in frown lines at 5 months based on physician assessment compared to 8% for placebo (secondary endpoint). In US studies, almost 5% of patients had a ≥2-grade improvement in frown lines at 5 months based on both patient and physician assessments compared to 0% for placebo (secondary endpoint). Results after day 30 or based on a 1-grade improvement may not be clinically meaningful.

If it’s your first time getting a treatment, you may be a little nervous and that’s okay! Localized pain, infection, inflammation, tenderness, swelling, erythema, and/or bleeding/bruising may be associated with the injection. For specific instructions on what to do before and after your treatment, please follow the instructions as given to you by your doctor or healthcare provider.

ell your healthcare provider about all your muscle or nerve conditions, such as ALS or Lou Gehrig’s disease, Myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects including difficulty swallowing and difficulty breathing from typical doses of Jeuveau.

Tell your healthcare provider about all your medical conditions, including: any side effects from botulinum toxin products, including dry eye; breathing, swallowing, bleeding, or heart problems; plans to have surgery; weakness of forehead muscles; drooping eyelids; have had surgery on your face; are pregnant or breastfeeding or plan to become pregnant or breastfeed (it is not known if Jeuveau can harm your unborn baby or passes into breast milk).

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using Jeuveau with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your healthcare provider that you have received Jeuveau in the past.

Especially tell your healthcare provider if you: have received any other botulinum toxin product in the past and the last 4 months, and exactly which product you received (such as BOTOX, BOTOX Cosmetic, MYOBLOC, DYSPORT, XEOMIN, or DAXXIFY).

Jeuveau lasts 4 months, on average, according to clinical trials, while Botox lasts 3 to 4 months. Longevity can vary by patient and dose. Typically, the higher the dose, the longer it lasts — up to a certain point. There is a margin of diminishing returns.